MESSAGE
DATE | 2020-05-07 |
FROM | Ruben Safir
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SUBJECT | Subject: [Hangout - NYLXS] Genomice Sequencing for Epidemiology
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https://genomeconnect.blogspot.com/2020/04/genome-sequencing-for-epidemiology.html
The declaration of COVID-19 as a global pandemic has necessitated the acute need for tools to be deployed for epidemiology, surveillance and molecular contact-tracing. The molecular tools for case detection have been heavily dependent on RT-PCR based methodologies, which target specific regions in the genome of SARS-nCoV-2, the viral pathogen causing COVID-19. While RT-PCR methods offer modest sensitivity and high specificity for case detection, they do not provide additional opportunities for understanding the molecular evolution of the virus.
Whole genome sequencing of SARS-nCoV-2 is now widely used across the globe to understand unique characteristics of the virus and also understand the origin of the virus. This is possible due to the fact that it is estimated that the virus has a modest mutation rate. As of date, over 10,000 whole genome sequences of SARS-nCoV-2 have been sequenced and deposited in public databases. The genome sequences provide the following additional opportunities and obviates some of the limitations of RT-PCR based assays.
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This work is largely coming out of india while we are inventing webboards and text messages.
-- So many immigrant groups have swept through our town that Brooklyn, like Atlantis, reaches mythological proportions in the mind of the world - RI Safir 1998 http://www.mrbrklyn.com DRM is THEFT - We are the STAKEHOLDERS - RI Safir 2002
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Being so tracked is for FARM ANIMALS and extermination camps, but incompatible with living as a free human being. -RI Safir 2013 _______________________________________________ Hangout mailing list Hangout-at-nylxs.com http://lists.mrbrklyn.com/mailman/listinfo/hangout
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