There are too many variables that computers and remote control can not cover. Pilots are needed for this reason. Even then accidents happen:
http://www.pilotfriend.com/disasters/crash/av_dsatrs.htm
http://en.wikipedia.org/wiki/List_of_accidents_and_incidents_involving_commercial_aircraft
Putting a pilot at the seat of the aircraft puts his life on the line and he will fly to the best to his ability and judgment to make sure that in the least, he survives the trip to collect a pay check. And computers can never replace people in certain tasks.
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From: Ruben Safir <mrbrklyn-at-panix.com>
Subject: [NYLXS - HANGOUT] fly without a pilot...sounds great
http://spectrum.ieee.org/aerospace/aviation/when-will-we-have-unmanned-commercial-airliners/0